The correct choice is to configure VNet peering with 'Allow gateway transit' and 'Use remote gateways' because this setup enables encrypted traffic between virtual networks in different regions while keeping the data path entirely over the Microsoft backbone, never traversing the public internet. VNet peering itself provides low-latency connectivity, but when you enable 'Use remote gateways', you force the traffic to route through a VPN gateway in the peered VNet, which applies IPsec encryption and ensures the traffic stays on Azure’s private network. On the Microsoft Cybersecurity Architect exam, this scenario tests your understanding of how to achieve encrypted inter-region VNet-to-VNet communication without relying on a separate VPN gateway or ExpressRoute circuit—common traps include confusing this with a site-to-site VPN (which uses the internet) or ExpressRoute (which connects on-premises, not VNets). Remember the key distinction: VNet peering is for VNet-to-VNet, and adding 'Use remote gateways' is the only way to encrypt that traffic over the backbone. A helpful mnemonic is “Peer then Encrypt with Remote Gateway” to recall that encryption is not native to peering itself.
SC-100 Design security solutions for infrastructure Practice Question
This SC-100 practice question tests your understanding of design security solutions for infrastructure. Match the stated requirement to the specific cloud service, access model, or configuration option — many options are valid in isolation but not for this scenario. After answering, compare your reasoning against the explanation and wrong-answer breakdown below. Once you have made your selection, read the full explanation to reinforce the concept and understand why each distractor is designed to mislead on exam day.
You are designing security for a multi-region Azure application. You need to ensure that traffic between virtual networks in different regions is encrypted and uses Microsoft backbone. What should you implement?
Answer the question above first, then reveal the full breakdown to understand why each option is right or wrong.
Correct answer & explanation
✓
Configure VNet peering with 'Allow gateway transit' and 'Use remote gateways'.
Option B is correct because VNet peering with 'Use Remote Gateway' enables encrypted transit over Microsoft backbone. Option A is wrong because VPN Gateway is for on-premises or inter-region VPN over internet, not using backbone. Option C is wrong because ExpressRoute is for on-premises to Azure, not VNet-to-VNet. Option D is wrong because Azure Firewall can inspect traffic but does not provide encrypted peering.
Key principle: Answer the scenario, not the keyword: identify the specific constraint before choosing the most familiar-sounding option.
Answer analysis
Option-by-option breakdown
For each option: why learners choose it and why it is or isn't the right answer here.
✓
Configure VNet peering with 'Allow gateway transit' and 'Use remote gateways'.
Why this is correct
VNet peering uses Microsoft backbone and can use VPNgateway for encryption if needed.
Related concept
Read the scenario before looking for a memorised answer.
✗
Use Azure Firewall in each VNet and route traffic through it.
Deploy ExpressRoute circuits and connect each VNet to them.
Why it's wrong here
ExpressRoute is for on-premises connectivity, not VNet-to-VNet.
✗
Deploy a site-to-site VPN between the virtual networks.
Why it's wrong here
Site-to-site VPN goes over the internet, not Microsoft backbone.
Common exam traps
Common exam trap: answer the scenario, not the keyword
Many certification questions include familiar terms but test a specific constraint. Read the exact wording before choosing an answer that is generally true but wrong for this case.
Detailed technical explanation
How to think about this question
This question should be treated as a scenario, not a definition check. Identify the problem, the constraint and the best action. Then compare each option against those facts.
KKey Concepts to Remember
Read the scenario before looking for a memorised answer.
Find the constraint that changes the correct option.
Eliminate answers that are true in general but not in this case.
Use explanations to understand the rule behind the answer.
TExam Day Tips
→Underline the problem statement mentally.
→Watch for words such as best, first, most likely and least administrative effort.
→Review why wrong options are wrong, not only why the correct option is correct.
Key takeaway
Answer the scenario, not the keyword: identify the specific constraint before choosing the most familiar-sounding option.
Real-world example
How this comes up in practice
A healthcare organisation deploys an application with a public-facing web tier and a private database tier. The database subnet has no public IP and only accepts connections from the web tier's security group. Questions like this test whether you can design cloud network isolation using VNets/VPCs, subnets, and security group rules.
Related glossary terms
Concepts from this question explained
These glossary pages explain the core terms tested in this SC-100 question in full detail.
Identify which SC-100 exam domain this question belongs to, then review the specific concept being tested. Practise related questions in that domain and focus on understanding why each wrong answer is tempting — not just why the correct answer is right.
Design security solutions for infrastructure — This question tests Design security solutions for infrastructure — Read the scenario before looking for a memorised answer..
What is the correct answer to this question?
The correct answer is: Configure VNet peering with 'Allow gateway transit' and 'Use remote gateways'. — Option B is correct because VNet peering with 'Use Remote Gateway' enables encrypted transit over Microsoft backbone. Option A is wrong because VPN Gateway is for on-premises or inter-region VPN over internet, not using backbone. Option C is wrong because ExpressRoute is for on-premises to Azure, not VNet-to-VNet. Option D is wrong because Azure Firewall can inspect traffic but does not provide encrypted peering.
What should I do if I get this SC-100 question wrong?
Identify which SC-100 exam domain this question belongs to, then review the specific concept being tested. Practise related questions in that domain and focus on understanding why each wrong answer is tempting — not just why the correct answer is right.
What is the key concept behind this question?
Read the scenario before looking for a memorised answer.
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Question Discussion
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