350-701 Practice Question: Secure Network Access, Visibility and Enforcement
Which protocol does Cisco ISE use to communicate with the pxGrid controller for sharing contextual data?
⚠ Common exam trap
Cisco often tests the distinction between pxGrid communication (JSON-RPC over TLS) and other ISE APIs (REST over HTTPS), leading candidates to mistakenly choose REST API because they associate HTTPS with secure data exchange.
Answer choices
Why each option matters
Answer the question above first, then reveal the full breakdown to understand why each option is right or wrong.
Correct answer & explanation
✓
JSON-RPC over certificate-based TLS
Cisco ISE uses the JSON-RPC protocol over certificate-based TLS to communicate with the pxGrid controller for sharing contextual data. This ensures encrypted, authenticated, and structured messaging between ISE and other pxGrid-enabled services, such as Cisco Threat Response or third-party integrations.
Answer analysis
Option-by-option breakdown
For each option: why learners choose it and why it is or isn't the right answer here.
- ✓
JSON-RPC over certificate-based TLS
Why this is correct
pxGrid uses JSON-RPC over TLS with mutual certificate authentication.
- ✗
REST API over HTTPS
Why it's wrong here
REST API is used for other ISE integrations, not pxGrid.
- ✗
TACACS+
Why it's wrong here
TACACS+ is for device administration, not pxGrid.
- ✗
RADIUS
Why it's wrong here
RADIUS is for authentication, not pxGrid.
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Written by Johnson Ajibi, MSc IT Security
Senior Network & Security Engineer · founder of Courseiva
This 350-701 practice question is part of Courseiva's free Cisco certification practice question bank. Courseiva provides original exam-style practice questions with explanations, topic-based practice, mock exams, readiness tracking, and study analytics to help learners prepare for the 350-701 exam.